Book Name: Biotransformations in Organic Chemistry: A Textbook 7th Edition
Author: Kurt Faber (auth.)
Publisher: Springer International Publishing
File size: 13 Mb
File format: PDF
Biotransformations in Organic Chemistry: A Textbook 7th Edition Pdf Book Description:
This well-established post on biocatalysis provides a foundation for graduate and undergraduate classes in modern organic chemistry, in addition to a condensed introduction into this subject. Following a simple introduction to the usage of biocatalysts–fundamentals of stereoselective transformations, enzyme properties and kinetics–the several kinds of reactions are explained in accordance with the’response principle’, including hydrolysis, reduction, oxidation, C–C bond formation, etc.. Special methods, like the use of enzymes in organic solvents, immobilization methods, artificial enzymes and also the plan of both cascade-reactions are treated in a distinct section. A last chapter addresses the basic principles for the practical and safe management of biocatalysts.
The use of biocatalysts, used either as isolated enzymes or whole microbial cells, provides a remarkable arsenal of highly selective transformations for innovative artificial organic chemistry. Over the previous two decades, this methodology is now an essential tool for asymmetric synthesis, but not just in the academic level, but also within a industrial scale. In this 7th edition new themes are introduced that include alcohol and amine oxidases, amine dehydrogenases, imine reductases, haloalkane dehalogenases, ATP-independent phosphorylation, Michael-additions and cascade reactions. This new edition also highlights the use of enzymes in industrial biotransformations with realistic cases.